CPNE9

Across TCGA patient cohorts, CPNE9 mutation is significantly associated with the RNA expression of many other genes, with 688 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible CPNE9-associated genes across cancer lineages are DEFB104A, RN7SKP65, and LSP1P3. Each is linked with CPNE9 in more than 1 cancer types. Because this analysis shows association rather than direction, both CPNE9-to-partner and partner-to-CPNE9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DEFB104A grouped by CPNE9-low versus CPNE9-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CPNE9→partner) and Y-score (partner→CPNE9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	DEFB104A →	+0.370	+5.010	<.001	.009	3	2
CESC	RN7SKP65 →	+0.246	+5.103	<.001	.008	3	2
UCEC	LSP1P3 →	+0.258	+1.870	<.001	.008	3	2
UCEC	UTP15 →	+0.432	+3.708	.002	<.001	3	2
SKCM	NBPF5P →	+0.038	+2.279	<.001	<.001	3	2
SKCM	SBF2-AS1 →	+0.419	+1.938	.008	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 688 associations by consensus.

DEFB104A by CPNE9 expression — CESC

Explore this box plot interactively →