CPNE9

Across TCGA pan-cancer cohorts, CPNE9 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated CPNE9 data layer compared with 2 for mutation status.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher CPNE9 RNA is associated with better overall survival. In most high-consensus cancer types, elevated CPNE9 expression acts as an unfavorable survival marker, although some lineages such as STAD and PAAD show a favorable association.

STAD, PAAD, and SKCM are the cancer types where CPNE9 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	OS	Median	IV	0.621	0.179	.003	82	view →
PAAD	OS	Tertile	All	0.608	0.273	<.001	72	view →
SKCM	OS	Tertile	II,III,IV	0.453	0.218	.001	44	view →
KIRP	DFS	Quartile	All	0.536	0.931	.014	38	view →
DLBC	DFS	Tertile	All	0.951	0.475	<.001	28	view →
MESO	OS	Quartile	All	0.669	0.426	.006	26	view →
LIHC	OS	Quartile	All	0.494	0.741	.001	24	view →
KIRC	DFS	Quartile	All	0.551	0.745	.005	23	view →
PRAD	DFS	Quartile	All	0.730	0.937	<.001	22	view →
COAD	OS	Quartile	IV	1.000	0.349	.002	20	view →
LUSC	DFS	Tertile	II,III,IV	0.655	0.826	.008	19	view →
BRCA	DFS	Median	All	0.931	0.967	<.001	19	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

CPNE9–STAD (OS)

Open the STAD breakdown →