CPNE9

Across TCGA cell cohorts, CPNE9 mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CPNE9-associated genes across cancer lineages are KLHDC7B, LMOD2, and ACSM6. Each is linked with CPNE9 in more than 1 cancer types. Because this analysis shows association rather than direction, both CPNE9-to-partner and partner-to-CPNE9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KLHDC7B grouped by CPNE9-low versus CPNE9-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CPNE9→partner) and Y-score (partner→CPNE9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	KLHDC7B →	+0.513	+3.485	.002	.004	3	1
LARGE_INTESTINE	LMOD2 →	+0.170	+3.643	<.001	.005	3	1
LARGE_INTESTINE	ACSM6 →	+0.016	+3.000	.005	.005	3	1
LARGE_INTESTINE	CHRNA9 →	+0.434	+3.963	.005	.001	3	1
LARGE_INTESTINE	ZNF732 →	+0.134	+3.466	.006	.005	3	1
LARGE_INTESTINE	CCER1 →	+0.008	+3.240	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

KLHDC7B by CPNE9 expression — LARGE_INTESTINE

Explore this box plot interactively →