CPNE8-AS1

Across TCGA pan-cancer cohorts, CPNE8-AS1 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated CPNE8-AS1 data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher CPNE8-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated CPNE8-AS1 expression acts as an unfavorable survival marker, although some lineages such as ESCA and UCS show a favorable association.

BLCA, UVM, and LGG are the cancer types where CPNE8-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	DFS	Quartile	All	0.420	0.588	.002	57	view →
UVM	DFS	Median	III,IV	0.326	0.740	<.001	52	view →
LGG	DFS	Median	All	0.675	0.794	<.001	48	view →
LAML	DFS	Median	All	0.403	0.724	<.001	42	view →
UCEC	OS	Tertile	All	0.601	0.849	.009	42	view →
KIRC	DFS	Tertile	All	0.817	0.910	.003	40	view →
ACC	OS	Median	II,III,IV	0.391	0.750	.005	33	view →
STAD	DFS	Tertile	All	0.567	0.725	.003	32	view →
PAAD	OS	Median	II,III,IV	0.372	0.603	.007	27	view →
ESCA	OS	Quartile	All	1.000	0.364	.006	21	view →
UCS	OS	Quartile	All	0.772	0.383	.007	16	view →
SKCM	DFS	Median	II,III,IV	0.185	0.284	.012	15	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

CPNE8-AS1–BLCA (DFS)

Open the BLCA breakdown →