CPNE8-AS1

Across TCGA pan-cancer cohorts, CPNE8-AS1 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of CPNE8-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where CPNE8-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types CPNE8-AS1 is over-expressed in tumor, although a few such as KICH and COAD show the opposite, repressed pattern.

KICH, COAD, and THCA are the cancer types where CPNE8-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CPNE8-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Female	III,IV	−2.630	<.001	11	view →
COAD	Female	II,III,IV	−0.854	<.001	10	view →
THCA	Male	III,IV	−1.052	<.001	9	view →
HNSC	All	IV	+0.758	<.001	8	view →
KIRC	Male	IV	+0.732	<.001	8	view →
BRCA	All	III,IV	−0.601	<.001	6	view →
BLCA	All	IV	−0.990	.005	4	view →
LUAD	Female	All	+0.384	.009	4	view →
PAAD	All	All	+0.620	.021	2	view →
UCEC	All	All	−0.590	.021	2	view →
PRAD	All	All	−0.280	.001	2	view →
READ	All	II,III,IV	−0.772	.018	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

CPNE8-AS1–KICH

Open the KICH breakdown →