CPNE7

Across TCGA cell cohorts, CPNE7 mutation is significantly associated with the drug of many other genes, with 29 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CPNE7-associated genes across cancer lineages are Luminespib, PCI-34051, and Temozolomide. Each is linked with CPNE7 in more than 1 cancer types. Because this analysis shows association rather than direction, both CPNE7-to-partner and partner-to-CPNE7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Luminespib grouped by CPNE7-low versus CPNE7-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CPNE7→partner) and Y-score (partner→CPNE7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Luminespib →	+0.609	+2.646	.046	.047	3	1
LARGE_INTESTINE	PCI-34051 →	+0.465	+2.646	.014	.047	3	1
BLOOD_Leukemia	Temozolomide →	-0.379	-2.964	.012	.029	3	1
BLOOD_Leukemia	FGFR_0939 →	+0.260	+2.999	.049	.028	3	1
BLOOD_Leukemia	IAP_5620 →	+0.733	+3.047	.001	.012	3	1
BLOOD_Leukemia	I-BET-762 →	-0.365	-3.000	.039	.028	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

Luminespib by CPNE7 expression — LARGE_INTESTINE

Explore this box plot interactively →