CPNE5

Across TCGA patient cohorts, CPNE5 mutation is significantly associated with the RNA expression of many other genes, with 3,546 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CPNE5-associated genes across cancer lineages are ARF1P1, ANKRD20A3P, and RN7SKP28. Each is linked with CPNE5 in more than 1 cancer types. Because this analysis shows association rather than direction, both CPNE5-to-partner and partner-to-CPNE5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ARF1P1 grouped by CPNE5-low versus CPNE5-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CPNE5→partner) and Y-score (partner→CPNE5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	ARF1P1 →	+0.096	+5.758	<.001	.003	3	2
HNSC	ANKRD20A3P →	+0.010	+4.536	<.001	.005	3	2
HNSC	RN7SKP28 →	+0.190	+4.578	<.001	.008	3	2
HNSC	MIR32 →	+0.522	+4.398	.001	.006	3	2
BRCA	RNY4P30 →	+0.214	+7.473	<.001	.007	3	2
BRCA	PPIAP27 →	+0.119	+4.760	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,546 associations by consensus.

ARF1P1 by CPNE5 expression — LIHC

Explore this box plot interactively →