CPNE3

Across TCGA patient cohorts, CPNE3 protein abundance is significantly associated with the RNA expression of many other genes, with 8,504 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible CPNE3-associated genes across cancer lineages are TPD52, YWHAZ, and CHMP4C. Each is linked with CPNE3 in more than 5 cancer types. Because this analysis shows association rather than direction, both CPNE3-to-partner and partner-to-CPNE3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CPNE3 versus TPD52 in HNSC, with a Pearson correlation of 0.30.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CPNE3→partner) and Y-score (partner→CPNE3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	TPD52 →	+0.772	+0.209	<.001	.002	3	6
BRCA	YWHAZ →	+0.606	+0.308	<.001	<.001	3	6
HNSC	CHMP4C →	+0.866	+0.286	<.001	<.001	3	5
BRCA	STK3 →	+0.553	+0.272	<.001	.003	3	5
CCRCC	RIDA →	+0.630	+0.213	<.001	<.001	3	5
OV	E2F5 →	+0.760	+0.698	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,504 associations by consensus.

CPNE3 vs TPD52 — HNSC

Explore this scatter interactively →