CPNE2

Across TCGA patient cohorts, CPNE2 protein abundance is significantly associated with the RNA expression of many other genes, with 14,924 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible CPNE2-associated genes across cancer lineages are ESAM, GSN, and HEY1. Each is linked with CPNE2 in more than 5 cancer types. Because this analysis shows association rather than direction, both CPNE2-to-partner and partner-to-CPNE2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CPNE2 versus ESAM in OV, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CPNE2→partner) and Y-score (partner→CPNE2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ESAM →	+0.960	+0.396	<.001	.004	3	6
UCEC	GSN →	+0.989	+0.268	.002	.006	3	5
LSCC	HEY1 →	+1.182	+0.230	<.001	<.001	3	5
OV	UPP1 →	+0.930	+0.391	<.001	.001	3	5
BRCA	SLC12A4 →	+0.452	+0.208	<.001	.001	3	5
BRCA	SPRY2 →	+0.877	+0.315	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,924 associations by consensus.

CPNE2 vs ESAM — OV

Explore this scatter interactively →