CPN2

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CPN2 protein abundance is significantly associated with the RNA expression of many other genes, with 11,349 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CPN2-associated genes across cancer lineages are IL6, MEDAG, and MMP19. Each is linked with CPN2 in more than 8 cancer types. Because this analysis shows association rather than direction, both CPN2-to-partner and partner-to-CPN2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CPN2 versus IL6 in LSCC, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CPN2→partner) and Y-score (partner→CPN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCIL6 →+1.580+0.568<.001<.00139
COADMEDAG →+1.135+0.495<.001<.00137
GBMMMP19 →+1.218+0.457<.001<.00137
BRCALYVE1 →+1.385+0.644<.001<.00137
OVDIPK2B →+0.864+0.708<.001<.00137
OVSLC2A3 →+1.435+0.645<.001<.00137
Each partner links to its Q-omics profile. Showing the 6 strongest of 11,349 associations by consensus.

CPN2 vs IL6 — LSCC

Per-sample scatter of CPN2 vs IL6 in LSCC (Pearson r = 0.43).

Explore this scatter interactively →

Exploration