CPN2

Across TCGA patient cohorts, CPN2 mutation is significantly associated with the RNA expression of many other genes, with 3,344 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CPN2-associated genes across cancer lineages are RNU6-1158P, STOML2, and TOMM5. Each is linked with CPN2 in more than 2 cancer types. Because this analysis shows association rather than direction, both CPN2-to-partner and partner-to-CPN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1158P grouped by CPN2-low versus CPN2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CPN2→partner) and Y-score (partner→CPN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNU6-1158P →	+0.079	+2.444	<.001	.006	3	3
UCEC	STOML2 →	+0.431	+2.947	.003	<.001	3	3
UCEC	TOMM5 →	+0.534	+2.447	<.001	.001	3	3
UCEC	ZNF852 →	+0.312	+3.024	.003	<.001	3	2
UCEC	VWA1 →	-1.111	-2.796	<.001	<.001	3	2
UCEC	AKAP5 →	+0.408	+2.807	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,344 associations by consensus.

RNU6-1158P by CPN2 expression — SKCM

Explore this box plot interactively →