CPN2

Across TCGA cell cohorts, CPN2 RNA expression is significantly associated with the go_rna of many other GO terms, with 422 significant associations in total. CNS shows the largest number of these associations.

The most reproducible CPN2-associated GO terms across cancer lineages are Phosphatidylserine metabolic process, Positive regulation of peptidase activity, and Regulation of post-translational protein modification. Each is linked with CPN2 in more than 3 cancer types. Because this analysis shows association rather than direction, both CPN2-to-partner and partner-to-CPN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Phosphatidylserine metabolic process grouped by CPN2-low versus CPN2-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CPN2→partner) and Y-score (partner→CPN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Phosphatidylserine metabolic process →	+0.073	+0.051	.002	.003	3	4
LUNG_NSCLC_LUSC	Positive regulation of peptidase activity →	+0.201	+0.017	.003	.005	3	4
LUNG_NSCLC_LUSC	Regulation of post-translational protein modification →	+0.049	+0.023	.005	.004	3	4
CNS	Cellular response to zinc ion starvation →	-0.127	-0.124	<.001	.008	3	4
CNS	Response to zinc ion starvation →	-0.127	-0.124	<.001	.008	3	4
LUNG_SCLC	Protein secretion →	+0.068	+0.049	.001	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 422 associations by consensus.

Phosphatidylserine metabolic process by CPN2 expression — LUNG_SCLC

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