CPM

Across TCGA patient cohorts, CPM protein abundance is significantly associated with the RNA expression of many other genes, with 14,073 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CPM-associated genes across cancer lineages are APOE, RNU7-4P, and ITGAX. Each is linked with CPM in more than 5 cancer types. Because this analysis shows association rather than direction, both CPM-to-partner and partner-to-CPM results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CPM versus APOE in COAD, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CPM→partner) and Y-score (partner→CPM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	APOE →	+1.210	+0.215	.001	.009	3	6
UCEC	RNU7-4P →	+2.143	+1.045	<.001	<.001	3	6
COAD	ITGAX →	+0.792	+0.230	.004	.007	3	5
GBM	KLHL6 →	+0.712	+0.765	<.001	<.001	3	5
GBM	PRELID2P1 →	+0.616	+0.650	<.001	<.001	3	5
GBM	HMOX1 →	+1.132	+0.784	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,073 associations by consensus.

CPM vs APOE — COAD

Explore this scatter interactively →