CPM

Across TCGA cell cohorts, CPM RNA expression is significantly associated with the go_rna of many other GO terms, with 4,568 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CPM-associated GO terms across cancer lineages are Biological process involved in symbiotic interaction, Protein targeting, and Protein targeting to vacuole involved in autophagy. Each is linked with CPM in more than 11 cancer types. Because this analysis shows association rather than direction, both CPM-to-partner and partner-to-CPM results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Biological process involved in symbiotic interaction grouped by CPM-low versus CPM-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CPM→partner) and Y-score (partner→CPM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Biological process involved in symbiotic interaction →	+0.109	+2.489	.001	<.001	3	12
OESOPHAGUS	Protein targeting →	+0.049	+1.665	<.001	<.001	3	11
BONE	Protein targeting to vacuole involved in autophagy →	+0.237	+2.848	<.001	<.001	3	11
OESOPHAGUS	Process utilizing autophagic mechanism →	+0.063	+1.566	<.001	<.001	3	11
OESOPHAGUS	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.087	+1.754	<.001	<.001	3	11
OESOPHAGUS	Autophagy →	+0.063	+1.566	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,568 associations by consensus.

Biological process involved in symbiotic interaction by CPM expression — LIVER

Explore this box plot interactively →