CPLANE2

Across TCGA patient cohorts, CPLANE2 protein abundance is significantly associated with the RNA expression of many other genes, with 4,232 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CPLANE2-associated genes across cancer lineages are GGT1, C22orf31, and ACR. Each is linked with CPLANE2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CPLANE2-to-partner and partner-to-CPLANE2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CPLANE2 versus GGT1 in GBM, with a Pearson correlation of 0.59.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CPLANE2→partner) and Y-score (partner→CPLANE2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	GGT1 →	+0.333	+0.733	<.001	.001	3	1
GBM	C22orf31 →	+0.693	+0.566	<.001	.002	3	1
GBM	ACR →	+0.133	+0.558	.006	.002	3	1
GBM	PSMC1 →	-0.194	-0.662	.005	<.001	3	1
GBM	RP2 →	-0.872	-0.827	<.001	.001	3	1
GBM	RBM3 →	-0.512	-0.667	.002	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,232 associations by consensus.

CPLANE2 vs GGT1 — GBM

Explore this scatter interactively →