Across TCGA patient cohorts, CPLANE1 mutation is significantly associated with the RNA expression of many other genes, with 7,657 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CPLANE1-associated genes across cancer lineages are PTMAP4, IGHVII-46-1, and MCMBP. Each is linked with CPLANE1 in more than 4 cancer types. Because this analysis shows association rather than direction, both CPLANE1-to-partner and partner-to-CPLANE1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CPLANE1→partner) and Y-score (partner→CPLANE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	PTMAP4 →	+0.494	+3.204	.002	.009	3	5
BRCA	IGHVII-46-1 →	+0.417	+2.530	<.001	.008	3	4
UCEC	MCMBP →	+0.427	+1.568	<.001	<.001	3	4
BLCA	CYP4F27P →	+0.269	+2.290	<.001	<.001	3	4
STAD	MAD2L1 →	+0.703	+3.940	.003	<.001	3	4
UCEC	KIF11 →	+0.592	+1.421	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,657 associations by consensus.

Exploration

CPLANE1 survival (RNA) · tumor vs normal (RNA) · all CPLANE1 data types