Across TCGA patient cohorts, CPEB1 mutation is significantly associated with the RNA expression of many other genes, with 5,905 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CPEB1-associated genes across cancer lineages are RPS12P15, UBE2S, and COX7A2. Each is linked with CPEB1 in more than 2 cancer types. Because this analysis shows association rather than direction, both CPEB1-to-partner and partner-to-CPEB1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CPEB1→partner) and Y-score (partner→CPEB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RPS12P15 →	+0.091	+3.278	<.001	.005	3	3
UCEC	UBE2S →	+0.638	+1.769	<.001	<.001	3	3
UCEC	COX7A2 →	+0.462	+1.736	<.001	<.001	3	3
UCEC	MRPL37 →	+0.461	+1.736	<.001	<.001	3	3
UCEC	CDCA5 →	+0.782	+2.203	<.001	<.001	3	3
SKCM	BOLA3 →	+0.406	+2.719	.009	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,905 associations by consensus.

Exploration

CPEB1 survival (RNA) · tumor vs normal (RNA) · all CPEB1 data types