Across TCGA patient cohorts, CPEB1 mutation is significantly associated with the total protein of many other genes, with 61 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CPEB1-associated genes across cancer lineages are eIF4E, FASN, and FoxM1. Each is linked with CPEB1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CPEB1-to-partner and partner-to-CPEB1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CPEB1→partner) and Y-score (partner→CPEB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eIF4E →	+0.203	+2.115	.002	<.001	3	2
COAD	FASN →	+0.514	+2.815	.016	.036	3	2
UCEC	FoxM1 →	+0.259	+2.115	.001	<.001	3	2
UCEC	Gab2 →	+0.261	+1.137	.020	.041	3	2
UCEC	p38-MAPK →	-0.111	-1.680	.031	.042	3	2
UCEC	ASNS →	+0.364	+1.925	.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 61 associations by consensus.

Exploration

CPEB1 survival (RNA) · tumor vs normal (RNA) · all CPEB1 data types