CPEB1-AS1

Across TCGA pan-cancer cohorts, CPEB1-AS1 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated CPEB1-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher CPEB1-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated CPEB1-AS1 expression acts as an unfavorable survival marker, although some lineages such as UCS and PAAD show a favorable association.

KIRC, UCS, and READ are the cancer types where CPEB1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Tertile	All	0.506	0.700	<.001	136	view →
UCS	DFS	Median	II,III,IV	0.588	0.132	<.001	50	view →
READ	OS	Quartile	III,IV	0.551	0.933	.004	48	view →
UVM	DFS	Quartile	II,III,IV	0.587	0.923	.005	41	view →
PAAD	DFS	Quartile	All	0.453	0.148	<.001	33	view →
CHOL	DFS	Tertile	II,III,IV	0.787	0.104	.031	15	view →
SKCM	OS	Quartile	III,IV	0.600	0.287	.004	13	view →
DLBC	DFS	Median	All	0.399	0.863	.035	12	view →
TGCT	DFS	Tertile	All	0.943	0.688	.002	12	view →
LUSC	DFS	Quartile	III,IV	0.455	1.000	.013	12	view →
ACC	OS	Quartile	All	0.968	0.790	.021	10	view →
LIHC	OS	Tertile	III,IV	1.000	0.387	.029	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

CPEB1-AS1–KIRC (OS)

Open the KIRC breakdown →