CPEB1-AS1

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, CPEB1-AS1 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of CPEB1-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where CPEB1-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CPEB1-AS1 is over-expressed in tumor, although a few such as UCEC and BRCA show the opposite, repressed pattern.

KIRP, UCEC, and BRCA are the cancer types where CPEB1-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CPEB1-AS1 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
KIRPAllAll+0.077.0035view →
UCECAllAll−0.240<.0014view →
BRCAAllAll−0.028.0024view →
COADAllAll−0.025<.0014view →
BLCAMaleIV−0.140.0162view →
LUADFemaleAll−0.074.0312view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

CPEB1-AS1–KIRP

Tumor-vs-normal expression box plot for CPEB1-AS1 RNA in KIRP.

Open the KIRP breakdown →

Exploration