CPE

Across TCGA patient cohorts, CPE protein abundance is significantly associated with the RNA expression of many other genes, with 10,984 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible CPE-associated genes across cancer lineages are HADHAP1, MIR578, and GPRASP2. Each is linked with CPE in more than 6 cancer types. Because this analysis shows association rather than direction, both CPE-to-partner and partner-to-CPE results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CPE versus HADHAP1 in LUAD, with a Pearson correlation of 0.85.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CPE→partner) and Y-score (partner→CPE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	HADHAP1 →	+1.409	+1.203	<.001	<.001	3	7
LUAD	MIR578 →	+1.540	+0.978	<.001	<.001	3	6
BRCA	GPRASP2 →	+0.490	+0.588	.004	.008	3	4
HNSC	PBOV1 →	+0.582	+0.507	.007	<.001	3	4
BRCA	SLC7A8 →	+1.119	+0.588	<.001	.001	3	4
GBM	SEPTIN4 →	+1.089	+0.443	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,984 associations by consensus.

CPE vs HADHAP1 — LUAD

Explore this scatter interactively →