CPAMD8

Across TCGA patient cohorts, CPAMD8 mutation is significantly associated with the total protein of many other genes, with 76 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CPAMD8-associated genes across cancer lineages are GAPDH, Cyclin-B1, and PCNA. Each is linked with CPAMD8 in more than 3 cancer types. Because this analysis shows association rather than direction, both CPAMD8-to-partner and partner-to-CPAMD8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GAPDH grouped by CPAMD8-low versus CPAMD8-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CPAMD8→partner) and Y-score (partner→CPAMD8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	GAPDH →	+0.424	+1.288	.009	.035	3	4
UCEC	Cyclin-B1 →	+0.484	+1.544	.001	<.001	3	4
STAD	PCNA →	+0.332	+2.321	.003	.032	2	4
UCEC	STAT3_pY705 →	-0.226	-1.184	.001	.016	3	3
SKCM	CD49b →	+0.155	+0.856	.008	.024	3	3
COAD	eIF4E →	+0.162	+1.690	.005	.012	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 76 associations by consensus.

GAPDH by CPAMD8 expression — COAD

Explore this box plot interactively →