CPAMD8

Across TCGA cell cohorts, CPAMD8 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,361 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CPAMD8-associated GO terms across cancer lineages are Regulation of myoblast fusion, Negative regulation of myoblast fusion, and Regulation of macroautophagy. Each is linked with CPAMD8 in more than 11 cancer types. Because this analysis shows association rather than direction, both CPAMD8-to-partner and partner-to-CPAMD8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of myoblast fusion grouped by CPAMD8-low versus CPAMD8-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CPAMD8→partner) and Y-score (partner→CPAMD8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Regulation of myoblast fusion →	+0.145	+1.332	.002	.001	3	12
OESOPHAGUS	Negative regulation of myoblast fusion →	+0.165	+1.332	.002	.001	3	12
OESOPHAGUS	Regulation of macroautophagy →	+0.091	+1.241	<.001	<.001	3	12
OESOPHAGUS	Regulation of syncytium formation by plasma membrane fusion →	+0.123	+1.080	<.001	.004	3	12
OESOPHAGUS	Negative regulation of syncytium formation by plasma membrane fusion →	+0.163	+1.332	.002	.001	3	11
OESOPHAGUS	Cellular response to nutrient levels →	+0.067	+1.404	.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,361 associations by consensus.

Regulation of myoblast fusion by CPAMD8 expression — OESOPHAGUS

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