CPA6

Across TCGA cell cohorts, CPA6 RNA expression is significantly associated with the go_rna of many other GO terms, with 686 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CPA6-associated GO terms across cancer lineages are Gland development, Labyrinthine layer development, and Positive regulation of protein import into nucleus. Each is linked with CPA6 in more than 4 cancer types. Because this analysis shows association rather than direction, both CPA6-to-partner and partner-to-CPA6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Gland development grouped by CPA6-low versus CPA6-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CPA6→partner) and Y-score (partner→CPA6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Gland development →	+0.051	+0.694	<.001	.007	3	5
LUNG_NSCLC_LUSC	Labyrinthine layer development →	+0.186	+0.795	.008	.003	3	5
CNS	Positive regulation of protein import into nucleus →	+0.069	+1.064	<.001	.003	3	5
LUNG_NSCLC_LUAD	Toll-like receptor 2 signaling pathway →	-0.085	-0.261	.009	.006	2	5
OVARY	Basement membrane disassembly →	+1.073	+0.666	.001	.004	3	4
KIDNEY	Positive regulation of angiogenesis →	+0.102	+0.931	.006	.006	2	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 686 associations by consensus.

Gland development by CPA6 expression — LARGE_INTESTINE

Explore this box plot interactively →