CPA2

Across TCGA patient cohorts, CPA2 protein abundance is significantly associated with the RNA expression of many other genes, with 1,911 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible CPA2-associated genes across cancer lineages are PPIL2, ESS2, and SLC25A1. Each is linked with CPA2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CPA2-to-partner and partner-to-CPA2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CPA2 versus PPIL2 in PDAC, with a Pearson correlation of -0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CPA2→partner) and Y-score (partner→CPA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	PPIL2 →	-0.148	-0.677	.003	<.001	3	1
PDAC	ESS2 →	-0.162	-0.713	<.001	<.001	3	1
PDAC	SLC25A1 →	-0.239	-0.675	<.001	<.001	3	1
PDAC	LGALS2 →	+1.151	+0.816	<.001	<.001	3	1
PDAC	HPS4 →	-0.304	-0.887	.007	.001	3	1
PDAC	TRIOBP →	-0.350	-1.048	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,911 associations by consensus.

CPA2 vs PPIL2 — PDAC

Explore this scatter interactively →