CPA2

Across TCGA cell cohorts, CPA2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,601 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible CPA2-associated GO terms across cancer lineages are Cytoplasmic translation, Regulation of myoblast fusion, and Positive regulation of DNA-templated transcription, elongation. Each is linked with CPA2 in more than 5 cancer types. Because this analysis shows association rather than direction, both CPA2-to-partner and partner-to-CPA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytoplasmic translation grouped by CPA2-low versus CPA2-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CPA2→partner) and Y-score (partner→CPA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Cytoplasmic translation →	+0.090	+0.103	<.001	.004	3	6
LUNG_SCLC	Regulation of myoblast fusion →	+0.065	+0.646	.001	.001	3	6
UPPER_AERODIGESTIVE_TRACT	Positive regulation of DNA-templated transcription, elongation →	+0.077	+0.132	<.001	.005	3	5
UPPER_AERODIGESTIVE_TRACT	Negative regulation of syncytium formation by plasma membrane fusion →	+0.123	+0.118	.003	.006	3	5
UPPER_AERODIGESTIVE_TRACT	RNA splicing, via transesterification reactions →	+0.088	+0.188	<.001	.002	3	5
LUNG_SCLC	Mitochondrial electron transport, ubiquinol to cytochrome c →	+0.102	+1.064	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,601 associations by consensus.

Cytoplasmic translation by CPA2 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →