CPA1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CPA1 protein abundance is significantly associated with the RNA expression of many other genes, with 2,625 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible CPA1-associated genes across cancer lineages are REG1A, KCNJ15, and SHROOM1. Each is linked with CPA1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CPA1-to-partner and partner-to-CPA1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CPA1 versus REG1A in COAD, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CPA1→partner) and Y-score (partner→CPA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADREG1A →+5.656+1.283<.001.00632
PDACKCNJ15 →+1.040+1.104<.001<.00132
COADSHROOM1 →-0.939-0.986.002.00232
COADCCDC110 →+0.595+0.741.002.00732
PDACTRBV5-7 →+0.909+0.671<.001<.00132
COADMIR3131 →-2.022-0.838<.001.00832
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,625 associations by consensus.

CPA1 vs REG1A — COAD

Per-sample scatter of CPA1 vs REG1A in COAD (Pearson r = 0.45).

Explore this scatter interactively →

Exploration