CPA1

Across TCGA cell cohorts, CPA1 RNA expression is significantly associated with the go_rna of many other GO terms, with 835 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible CPA1-associated GO terms across cancer lineages are Positive regulation of DNA-templated transcription, elongation, Immune response-regulating cell surface receptor signaling pathway, and Development of primary male sexual characteristics. Each is linked with CPA1 in more than 3 cancer types. Because this analysis shows association rather than direction, both CPA1-to-partner and partner-to-CPA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of DNA-templated transcription, elongation grouped by CPA1-low versus CPA1-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CPA1→partner) and Y-score (partner→CPA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Positive regulation of DNA-templated transcription, elongation →	+0.049	+0.499	.007	.006	3	4
LUNG_SCLC	Immune response-regulating cell surface receptor signaling pathway →	-0.030	-0.424	.002	<.001	3	4
LUNG_SCLC	Development of primary male sexual characteristics →	-0.097	-0.547	<.001	.005	3	4
LUNG_NSCLC_LUSC	Regulation of cell division →	+0.051	+0.084	.005	.002	3	4
LUNG_SCLC	Male gonad development →	-0.101	-0.553	<.001	.005	3	4
SOFT_TISSUE	RNA-templated transcription →	+0.132	+0.910	.001	.002	2	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 835 associations by consensus.

Positive regulation of DNA-templated transcription, elongation by CPA1 expression — SOFT_TISSUE

Explore this box plot interactively →