Across TCGA pan-cancer cohorts, COX8C Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated COX8C data layer compared with 21 for mass-spec protein.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher COX8C Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated COX8C expression acts as an unfavorable survival marker.

STAD and LUSC are the cancer types where COX8C Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	OS	Median	All	0.003	0.667	<.001	24	view →
LUSC	OS	Median	All	0.172	0.762	.002	24	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: COX8C tumor-vs-normal RNA expression · all COX8C data types