COX8A

Across TCGA cell cohorts, COX8A protein abundance is significantly associated with the RNA expression of many other genes, with 1,254 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible COX8A-associated genes across cancer lineages are INAVA, TUT4, and IL36G. Each is linked with COX8A in more than 3 cancer types. Because this analysis shows association rather than direction, both COX8A-to-partner and partner-to-COX8A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COX8A versus INAVA in LARGE_INTESTINE, with a Pearson correlation of 0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COX8A→partner) and Y-score (partner→COX8A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	INAVA →	+1.388	+0.614	.004	<.001	3	4
PANCREAS	TUT4 →	-1.924	-0.663	.004	.003	3	4
BLOOD_Myeloma	IL36G →	+0.182	+1.240	.004	.005	3	4
STOMACH	RBX1 →	-1.251	-1.228	.003	.002	3	3
STOMACH	ANGEL1 →	+0.912	+0.849	<.001	.006	3	3
OVARY	EPS8 →	-2.018	-1.031	.002	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,254 associations by consensus.

COX8A vs INAVA — LARGE_INTESTINE

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