COX7A2

Across TCGA patient cohorts, COX7A2 mutation is significantly associated with the RNA expression of many other genes, with 22 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible COX7A2-associated genes across cancer lineages are MTND6P20, MIR4705, and MIR4438. Each is linked with COX7A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both COX7A2-to-partner and partner-to-COX7A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MTND6P20 grouped by COX7A2-low versus COX7A2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COX7A2→partner) and Y-score (partner→COX7A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MTND6P20 →	+0.104	+7.816	<.001	.008	3	1
SKCM	MIR4705 →	+0.748	+7.816	<.001	.008	3	1
SKCM	MIR4438 →	+0.378	+7.816	<.001	.008	3	1
SKCM	KYNUP2 →	+0.034	+7.816	<.001	.008	3	1
KIRC	TTTY1B →	+0.029	+8.025	<.001	.007	3	1
UCEC	RNU6-208P →	+0.493	+3.993	.003	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

MTND6P20 by COX7A2 expression — SKCM

Explore this box plot interactively →