COX7A1

Across TCGA patient cohorts, COX7A1 mutation is significantly associated with the RNA expression of many other genes, with 27 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible COX7A1-associated genes across cancer lineages are RNU6-1198P, OR4A49P, and FAM133GP. Each is linked with COX7A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both COX7A1-to-partner and partner-to-COX7A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1198P grouped by COX7A1-low versus COX7A1-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COX7A1→partner) and Y-score (partner→COX7A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	RNU6-1198P →	+0.925	+5.758	<.001	.003	3	1
LIHC	OR4A49P →	+0.082	+6.008	<.001	.002	3	1
LIHC	FAM133GP →	+0.102	+5.186	<.001	.007	3	1
LIHC	MIR3173 →	+0.717	+5.447	<.001	.005	3	1
LIHC	PPIAP56 →	+0.335	+5.355	<.001	.005	3	1
LIHC	OR5AN1 →	+0.096	+5.447	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

RNU6-1198P by COX7A1 expression — LIHC

Explore this box plot interactively →