COX6B2

Across TCGA patient cohorts, COX6B2 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible COX6B2-associated genes across cancer lineages are OFD1P11Y, RNY4P16, and RNU1-64P. Each is linked with COX6B2 in more than 1 cancer types. Because this analysis shows association rather than direction, both COX6B2-to-partner and partner-to-COX6B2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OFD1P11Y grouped by COX6B2-low versus COX6B2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COX6B2→partner) and Y-score (partner→COX6B2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	OFD1P11Y →	+0.039	+7.816	<.001	.008	3	1
SKCM	RNY4P16 →	+0.533	+7.816	<.001	.008	3	1
SKCM	RNU1-64P →	+0.198	+7.816	<.001	.008	3	1
SKCM	RNU6-281P →	+0.373	+7.816	<.001	.008	3	1
SKCM	MIR3152 →	+0.478	+7.816	<.001	.008	3	1
SKCM	MRPS5P4 →	+0.139	+7.816	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

OFD1P11Y by COX6B2 expression — SKCM

Explore this box plot interactively →