COX4I2

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, COX4I2 RNA expression is significantly associated with the go_rna of many other GO terms, with 428 significant associations in total. LIVER shows the largest number of these associations.

The most reproducible COX4I2-associated GO terms across cancer lineages are Positive regulation of intestinal absorption, Positive regulation of intestinal lipid absorption, and Regulation of leukocyte apoptotic process. Each is linked with COX4I2 in more than 1 cancer types. Because this analysis shows association rather than direction, both COX4I2-to-partner and partner-to-COX4I2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of intestinal absorption grouped by COX4I2-low versus COX4I2-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (COX4I2→partner) and Y-score (partner→COX4I2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
PANCREASPositive regulation of intestinal absorption →-0.223-0.029.001.00932
PANCREASPositive regulation of intestinal lipid absorption →-0.223-0.029.001.00932
PANCREASRegulation of leukocyte apoptotic process →+0.098+0.030<.001.00732
PANCREASPositive regulation of intestinal cholesterol absorption →-0.205-0.029<.001.00932
LIVERCellular response to environmental stimulus →-0.039-0.036.007.00532
LIVERRegulation of calcium ion transport into cytosol →-0.226-0.035.001.00432
Each partner links to its Q-omics profile. Showing the 6 strongest of 428 associations by consensus.

Positive regulation of intestinal absorption by COX4I2 expression — PANCREAS

Box plot of Positive regulation of intestinal absorption in COX4I2-low vs COX4I2-high samples in PANCREAS.

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Exploration