Across TCGA patient cohorts, COX20 mutation is significantly associated with the RNA expression of many other genes, with 1,564 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible COX20-associated genes across cancer lineages are OR9Q2, MIR8062, and IGHV1OR15-6. Each is linked with COX20 in more than 1 cancer types. Because this analysis shows association rather than direction, both COX20-to-partner and partner-to-COX20 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COX20→partner) and Y-score (partner→COX20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	OR9Q2 →	+0.097	+6.721	<.001	<.001	3	2
BRCA	MIR8062 →	+0.394	+7.471	<.001	.008	3	1
UCEC	IGHV1OR15-6 →	+0.250	+2.734	<.001	.001	3	1
UCEC	IGHV3OR16-8 →	+0.778	+2.687	.001	.001	3	1
UCEC	IGHV3OR16-13 →	+0.760	+2.481	<.001	.002	3	1
UCEC	IGKV1OR2-6 →	+0.747	+2.163	.007	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,564 associations by consensus.

Exploration

COX20 survival (RNA) · tumor vs normal (RNA) · all COX20 data types