COX17

Across TCGA cell cohorts, COX17 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,649 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible COX17-associated GO terms across cancer lineages are Cristae formation, Positive regulation of muscle cell differentiation, and Artery development. Each is linked with COX17 in more than 11 cancer types. Because this analysis shows association rather than direction, both COX17-to-partner and partner-to-COX17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cristae formation grouped by COX17-low versus COX17-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (COX17→partner) and Y-score (partner→COX17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Cristae formation →	+0.081	+0.888	.001	<.001	3	12
BLOOD_Leukemia	Positive regulation of muscle cell differentiation →	-0.109	-0.580	<.001	.001	3	9
SOFT_TISSUE	Artery development →	-0.089	-0.513	.001	.002	2	10
LUNG_NSCLC_LUAD	Ameboidal-type cell migration →	-0.073	-0.814	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Extracellular matrix organization →	-0.094	-0.731	.002	.002	3	9
BLOOD_Leukemia	Outflow tract septum morphogenesis →	-0.173	-0.712	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,649 associations by consensus.

Cristae formation by COX17 expression — OVARY

Explore this box plot interactively →