COX11

Across TCGA cell cohorts, COX11 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,677 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible COX11-associated GO terms across cancer lineages are Subtelomeric heterochromatin formation, Microtubule polymerization, and Positive regulation of mitotic cytokinesis. Each is linked with COX11 in more than 13 cancer types. Because this analysis shows association rather than direction, both COX11-to-partner and partner-to-COX11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Subtelomeric heterochromatin formation grouped by COX11-low versus COX11-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (COX11→partner) and Y-score (partner→COX11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Subtelomeric heterochromatin formation →	+0.144	+0.900	<.001	<.001	3	14
BONE	Microtubule polymerization →	+0.142	+1.306	<.001	<.001	3	14
BREAST	Positive regulation of mitotic cytokinesis →	+0.174	+1.404	<.001	<.001	3	14
BONE	Positive regulation of DNA-directed DNA polymerase activity →	+0.169	+0.888	<.001	<.001	3	13
BONE	Microtubule nucleation →	+0.156	+1.196	<.001	<.001	3	13
OESOPHAGUS	Nucleoside triphosphate biosynthetic process →	+0.144	+0.682	<.001	.003	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,677 associations by consensus.

Subtelomeric heterochromatin formation by COX11 expression — SOFT_TISSUE

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