COX10

Across TCGA cell cohorts, COX10 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,361 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible COX10-associated GO terms across cancer lineages are 'de novo' IMP biosynthetic process, rRNA methylation, and Mitochondrial ribosome assembly. Each is linked with COX10 in more than 13 cancer types. Because this analysis shows association rather than direction, both COX10-to-partner and partner-to-COX10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 'de novo' IMP biosynthetic process grouped by COX10-low versus COX10-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (COX10→partner) and Y-score (partner→COX10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	'de novo' IMP biosynthetic process →	+0.145	+0.725	<.001	<.001	3	14
LUNG_NSCLC_LUAD	rRNA methylation →	+0.071	+0.583	<.001	.002	3	13
LARGE_INTESTINE	Mitochondrial ribosome assembly →	+0.065	+0.709	<.001	<.001	3	12
OVARY	Heme biosynthetic process →	+0.104	+0.828	<.001	<.001	3	12
LUNG_SCLC	Cytochrome complex assembly →	+0.082	+0.738	.003	<.001	3	11
LUNG_NSCLC_LUSC	Heme A biosynthetic process →	+0.123	+0.466	.008	.003	2	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,361 associations by consensus.

'de novo' IMP biosynthetic process by COX10 expression — LARGE_INTESTINE

Explore this box plot interactively →