COX10-AS1

Across TCGA pan-cancer cohorts, COX10-AS1 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated COX10-AS1 data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher COX10-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated COX10-AS1 expression acts as an unfavorable survival marker, although some lineages such as BRCA and READ show a favorable association.

KICH, ACC, and KIRC are the cancer types where COX10-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Quartile	All	0.526	0.960	.001	44	view →
ACC	DFS	Quartile	All	0.191	0.821	<.001	41	view →
KIRC	DFS	Median	IV	0.224	0.421	.007	35	view →
BRCA	OS	Quartile	III,IV	0.689	0.381	.002	33	view →
COAD	DFS	Quartile	All	0.372	0.668	<.001	33	view →
READ	OS	Median	II,III,IV	0.841	0.307	<.001	29	view →
LGG	DFS	Tertile	All	0.781	0.888	.001	27	view →
SKCM	DFS	Quartile	All	0.235	0.114	.004	14	view →
PAAD	DFS	Quartile	All	0.418	0.120	.006	14	view →
SARC	DFS	Tertile	All	0.226	0.467	.011	12	view →
UVM	OS	Median	III,IV	0.281	1.000	.003	11	view →
DLBC	DFS	Tertile	All	0.727	1.000	.016	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

COX10-AS1–KICH (DFS)

Open the KICH breakdown →