Across TCGA patient cohorts, COTL1P2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,400 significant associations in total. STAD shows the largest number of these associations.

The most reproducible COTL1P2-associated GO terms across cancer lineages are Regulation of cysteine-type endopeptidase activity, Negative regulation of inflammatory response, and Anatomical structure maturation. Each is linked with COTL1P2 in more than 10 cancer types. Because this analysis shows association rather than direction, both COTL1P2-to-partner and partner-to-COTL1P2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (COTL1P2→partner) and Y-score (partner→COTL1P2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of cysteine-type endopeptidase activity →	+0.042	+0.158	<.001	<.001	3	10
STAD	Negative regulation of inflammatory response →	+0.028	+0.144	<.001	<.001	3	10
STAD	Anatomical structure maturation →	+0.024	+0.133	<.001	<.001	3	10
STAD	Regulation of protein serine/threonine kinase activity →	+0.038	+0.138	<.001	<.001	3	10
ESCA	Peptidyl-tyrosine modification →	+0.034	+0.119	.002	.003	3	10
STAD	Phosphatidylinositol 3-kinase/protein kinase B signal transduction →	+0.036	+0.146	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,400 associations by consensus.

Exploration

COTL1P2 survival (RNA) · tumor vs normal (RNA) · all COTL1P2 data types