COTL1P1

Across TCGA patient cohorts, COTL1P1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,836 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible COTL1P1-associated GO terms across cancer lineages are Adaptive thermogenesis, Protein complex oligomerization, and Neutral amino acid transport. Each is linked with COTL1P1 in more than 7 cancer types. Because this analysis shows association rather than direction, both COTL1P1-to-partner and partner-to-COTL1P1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Adaptive thermogenesis grouped by COTL1P1-low versus COTL1P1-high in UCEC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (COTL1P1→partner) and Y-score (partner→COTL1P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Adaptive thermogenesis →	+0.027	+0.046	<.001	<.001	3	8
UCEC	Protein complex oligomerization →	+0.023	+0.036	<.001	<.001	3	7
LAML	Neutral amino acid transport →	+0.040	+0.227	<.001	<.001	3	7
LAML	Positive regulation of endocytosis →	+0.042	+0.260	<.001	<.001	3	7
ESCA	Regulation of small GTPase mediated signal transduction →	+0.029	+0.046	.008	<.001	3	7
ESCA	Neutral lipid metabolic process →	+0.028	+0.056	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,836 associations by consensus.

Adaptive thermogenesis by COTL1P1 expression — UCEC

Explore this box plot interactively →