CORT

Across TCGA cell cohorts, CORT mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CORT-associated genes across cancer lineages are OR10G2. Each is linked with CORT in more than 1 cancer types. Because this analysis shows association rather than direction, both CORT-to-partner and partner-to-CORT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10G2 grouped by CORT-low versus CORT-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CORT→partner) and Y-score (partner→CORT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	OR10G2 →	+0.043	+4.977	.008	.007	3	1

Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

OR10G2 by CORT expression — LARGE_INTESTINE

Explore this box plot interactively →