CORO2B

Across TCGA patient cohorts, CORO2B mutation is significantly associated with the RNA expression of many other genes, with 5,143 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CORO2B-associated genes across cancer lineages are OR2Z1, STX5, and DHDDS. Each is linked with CORO2B in more than 2 cancer types. Because this analysis shows association rather than direction, both CORO2B-to-partner and partner-to-CORO2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR2Z1 grouped by CORO2B-low versus CORO2B-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CORO2B→partner) and Y-score (partner→CORO2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	OR2Z1 →	+0.104	+5.544	<.001	.004	3	3
UCEC	STX5 →	+0.305	+2.601	.003	<.001	3	3
UCEC	DHDDS →	+0.502	+2.389	<.001	<.001	3	3
UCEC	CCNB1 →	+0.815	+3.857	<.001	<.001	3	3
UCEC	TXNL4A →	+0.295	+1.820	.007	.001	3	3
LIHC	RPL23AP40 →	+0.250	+5.186	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,143 associations by consensus.

OR2Z1 by CORO2B expression — LIHC

Explore this box plot interactively →