CORO2B

Across TCGA cell cohorts, CORO2B mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible CORO2B-associated genes across cancer lineages are SPACA1, HCRTR2, and CARTPT. Each is linked with CORO2B in more than 1 cancer types. Because this analysis shows association rather than direction, both CORO2B-to-partner and partner-to-CORO2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SPACA1 grouped by CORO2B-low versus CORO2B-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CORO2B→partner) and Y-score (partner→CORO2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	SPACA1 →	+0.010	+4.266	<.001	.004	3	1
LUNG_NSCLC_LUAD	HCRTR2 →	+0.342	+3.736	<.001	.004	3	1
LUNG_NSCLC_LUAD	CARTPT →	+0.011	+4.266	<.001	.004	3	1
LUNG_NSCLC_LUAD	OR56A3 →	+0.561	+3.343	.006	.005	3	1
LARGE_INTESTINE	ACER1 →	+0.068	+2.560	.006	.009	1	1
LARGE_INTESTINE	ZCWPW2 →	+0.249	+3.285	<.001	.007	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

SPACA1 by CORO2B expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →