CORO2A

Across TCGA cell cohorts, CORO2A RNA expression is significantly associated with the go_rna of many other GO terms, with 3,899 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible CORO2A-associated GO terms across cancer lineages are ERBB3 signaling pathway, ERBB2-ERBB3 signaling pathway, and Negative regulation of myoblast fusion. Each is linked with CORO2A in more than 9 cancer types. Because this analysis shows association rather than direction, both CORO2A-to-partner and partner-to-CORO2A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ERBB3 signaling pathway grouped by CORO2A-low versus CORO2A-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CORO2A→partner) and Y-score (partner→CORO2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	ERBB3 signaling pathway →	+0.130	+1.050	<.001	.003	3	10
LUNG_NSCLC_LUAD	ERBB2-ERBB3 signaling pathway →	+0.130	+1.050	<.001	.003	3	10
KIDNEY	Negative regulation of myoblast fusion →	+0.134	+1.278	<.001	<.001	3	9
OVARY	Negative regulation of syncytium formation by plasma membrane fusion →	+0.125	+1.548	<.001	<.001	3	9
KIDNEY	Regulation of protein localization to nucleus →	+0.086	+1.257	<.001	<.001	3	9
LUNG_NSCLC_LUAD	Golgi vesicle budding →	+0.120	+1.617	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,899 associations by consensus.

ERBB3 signaling pathway by CORO2A expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →