CORO2A

Across TCGA cell cohorts, CORO2A mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CORO2A-associated genes across cancer lineages are GPR101, OR1A2, and RNASE9. Each is linked with CORO2A in more than 1 cancer types. Because this analysis shows association rather than direction, both CORO2A-to-partner and partner-to-CORO2A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GPR101 grouped by CORO2A-low versus CORO2A-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CORO2A→partner) and Y-score (partner→CORO2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	GPR101 →	+0.022	+4.887	<.001	.009	3	1
LUNG_NSCLC_LUAD	OR1A2 →	+0.023	+6.266	<.001	<.001	3	1
LUNG_NSCLC_LUAD	RNASE9 →	+0.011	+4.887	.009	.009	3	1
LUNG_NSCLC_LUAD	OR1P1 →	+0.055	+4.887	<.001	.009	3	1
LARGE_INTESTINE	FAM205A →	+0.017	+3.029	<.001	.003	3	1
LARGE_INTESTINE	PTTG2 →	+0.088	+3.497	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

GPR101 by CORO2A expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →