CORO1A

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, CORO1A Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated CORO1A data layer compared with 24 for mass-spec protein and 7 for mass-spec protein.

The strongest signal is observed in small cell lung cancer (SCLC), where higher CORO1A Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated CORO1A expression acts as an unfavorable survival marker.

SCLC and STAD are the cancer types where CORO1A Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
SCLCDFSMedianIII,IV0.1370.546.0426view →
STADOSMedianIII,IV0.4230.634.0024view →
Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

CORO1A–SCLC (DFS)

Kaplan–Meier survival curve for CORO1A mutant vs wild-type samples in SCLC.

Open the SCLC breakdown →

Exploration