CORO1A

Across TCGA cell cohorts, CORO1A RNA expression is significantly associated with the go_rna of many other GO terms, with 3,658 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CORO1A-associated GO terms across cancer lineages are Natural killer cell activation involved in immune response, Natural killer cell degranulation, and Regulation of chromosome organization. Each is linked with CORO1A in more than 10 cancer types. Because this analysis shows association rather than direction, both CORO1A-to-partner and partner-to-CORO1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Natural killer cell activation involved in immune response grouped by CORO1A-low versus CORO1A-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CORO1A→partner) and Y-score (partner→CORO1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Natural killer cell activation involved in immune response →	+0.338	+1.486	<.001	<.001	3	11
LUNG_SCLC	Natural killer cell degranulation →	+0.340	+1.651	<.001	<.001	3	11
SKIN	Regulation of chromosome organization →	+0.067	+1.063	<.001	.001	3	9
OESOPHAGUS	Regulation of mitotic metaphase/anaphase transition →	+0.132	+1.326	.002	.005	3	8
OESOPHAGUS	Regulation of sister chromatid segregation →	+0.125	+1.410	.003	.003	3	8
OESOPHAGUS	Regulation of chromosome segregation →	+0.128	+1.510	.003	.003	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,658 associations by consensus.

Natural killer cell activation involved in immune response by CORO1A expression — LUNG_SCLC

Explore this box plot interactively →