CORO1A

Across TCGA cell cohorts, CORO1A mutation is significantly associated with the RNA expression of many other genes, with 19 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CORO1A-associated genes across cancer lineages are PRR23B, LILRA1, and BPIFA1. Each is linked with CORO1A in more than 1 cancer types. Because this analysis shows association rather than direction, both CORO1A-to-partner and partner-to-CORO1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRR23B grouped by CORO1A-low versus CORO1A-high in STOMACH.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CORO1A→partner) and Y-score (partner→CORO1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	PRR23B →	+0.010	+4.285	<.001	.007	3	2
LARGE_INTESTINE	LILRA1 →	+0.013	+4.095	.001	.009	3	1
LARGE_INTESTINE	BPIFA1 →	+0.178	+4.273	<.001	.006	3	1
SKIN	MBD3L5 →	+0.032	+5.415	<.001	.004	3	1
SKIN	OR5V1 →	+0.016	+4.977	<.001	.007	3	1
BLOOD_Leukemia	APOL5 →	+0.013	+3.475	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

PRR23B by CORO1A expression — STOMACH

Explore this box plot interactively →