COQ6

Across TCGA patient cohorts, COQ6 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,473 significant associations in total. GBM shows the largest number of these associations.

The most reproducible COQ6-associated proteins across cancer lineages are PPP2R5E, UBR7, and MTA1. Each is linked with COQ6 in more than 6 cancer types. Because this analysis shows association rather than direction, both COQ6-to-partner and partner-to-COQ6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COQ6 versus PPP2R5E in PDAC, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (COQ6→partner) and Y-score (partner→COQ6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	PPP2R5E →	+0.398	+0.322	<.001	<.001	3	7
OV	UBR7 →	+0.504	+0.441	<.001	<.001	3	7
GBM	MTA1 →	+0.492	+0.373	<.001	<.001	3	6
PDAC	MTA1_S576 →	+0.631	+0.312	<.001	<.001	3	6
GBM	MTHFD1 →	+0.346	+0.416	<.001	<.001	3	6
BRCA	NEK9 →	+0.310	+0.556	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,473 associations by consensus.

COQ6 vs PPP2R5E — PDAC

Explore this scatter interactively →